If you are running into some weird profile corruption problems or random loss of data within a Provisioned image this could very well be the reason why.
With the new release of PVS 6, there are already a good number of reported hotfixes. Of particular attention is the last patch listed below which can make PVS stop working all-together
Knowing that it is difficult to keep track of hotfixes that are sometimes not even listed under the Citrix support site, I decided to compile my own list of current hotfixes.